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 万江陵1963年出生,副教授,硕士生导师,国家纳米药物工程技术研究中心总工程师,华中科技大学生命科学与技术学院纳米与生物制药系副主任。1987年本科毕业于华西医科大学药学院,2003年获湖北大学有机化学专业硕士学位。

近十年来主要从事药物设计和药物纳米制剂的研究,作为主要研究人员参加了国家973项目、国家863项目等项目的研究工作,主持应用研究项目多项,先后获湖北省科技进步一等奖、化工部科技进步三等奖各1次,获国家专利授权2项(其中1项排名第一),参编纳米药物专著2部(《纳米药物》、《纳米药物安全性》)。

5年发表的重要SCI论文(带“*”为通讯作者或共同第一作者)

[1] Chen Siyuan, Liu Wei, Wan Jiangling, Cheng Xin, Gu Conghui, Zhou Hui, Chen Shan, Zhao Xiaojing, Tang Yuxiang, Yang Xiangliang. Preparation of Coenzyme Q10 nanostructured lipid carriers for epidermal targeting with high-pressure microfluidics technique. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2013,39(1):20-28.

[2] Zhang Zhen, Xiong Xiaoqin, Wan Jiangling*, Xiao Ling, Gan Lu, Feng Youmei, Xu Huibi, Yang Xiangliang. Cellular uptake and intracellular trafficking of PEG-b-PLA polymeric micelles. BIOMATERIALS, 2012,33(29):7233-7240.

[3] Leng Fujian, Wan Jiangling, Liu Wei, Tao Bo, Chen Xuehong. Prolongation of Epidural Analgesia Using Solid Lipid Nanoparticles as Drug Carrier for Lidocaine. REGIONAL ANESTHESIA AND PAIN MEDICINE, 2012,37(2):159-165.

[4]  Mou Dongsheng, Chen Huabing, Wan Jiangling, Xu Huibi, Yang Xiangliang. Potent dried drug nanosuspensions for oral bioavailability enhancement of poorly soluble drugs with pH-dependent solubility. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2011,413(1-2):237-244.

[5] Chen Huabing, Zhu Hongda, Hu Jingdong, Zhao Yanbing, Wang Qin, Wan Jiangling, Yang Yajiang, Xu Huibi, Yang Xiangliang. Highly Compressed Assembly of Deformable Nanogels into Nanoscale Suprastructures and Their Application in Nanomedicine. ACS NANO,2011,5(4):2671-2680.

[6] Mao Chengwen, Wan Jiangling, Chen Huabing, Xu Huibi, Yang Xiangliang. The composition of oil phase modulates venous irritation of lipid emulsion-loaded diallyl trisulfide. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2010, 36(6):698-704.

[7] Chen Huabing, Zhu Hongda, Zheng Jingnan, Mou Dongsheng, Wan Jiangling, Zhang Junyong, Shi Tielin, Zhao Yingjun, Xu Huibi, Yang Xiangliang. Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin. JOURNAL OF CONTROLLED RELEASE, 2009,139(1):63-72.

[8] Mao Chengwen, Wan Jiangling, Chen Huabing, Xu Huibi, Yang Xiangliang. Emulsifiers' Composition Modulates Venous Irritation of the Nanoemulsions as a Lipophilic and Venous Irritant Drug Delivery System. AAPS PHARMSCITECH,2009(10):1058-1064.

[9] Zhao Xiaozhi, Mou Dongsheng, Wan Jiangling, Xu Huibi, Yang Xiangliang.A novel method for the separation and determination of non-encapsulated pyrene in plasma and its application in pharmacokinetic studies of pyrene-loaded MPEG-PLA based nanoparticles. NANOTECHNOLOGY, 2009,20(12):125701.

[10] Wang Wei, Xiong Wei, Wan Jiangling, Sun Xiaohui, Xu Huibi, Yang Xiangliang. The decrease of PAMAM dendrimer-induced cytotoxicity by PEGylation via attenuation of oxidative stress. NANOTECHNOLOGY, 2009,20(10):105103.

[11] Zhao Xiaozhi, Wan Jiangling, Xu Huibi, Yang Xiangliang. An improved HPLC method with fluorescence detection for the determination of pyrene in rat plasma and its pharmacokinetics. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2008,48(4):1237-1242.

[12] Yi Tao, Wan Jiangling, Xu Huibi, Yang Xiangliang. A new solid self-microemulsifying formulation prepared by spray-drying to improve the oral bioavailability of poorly water soluble drugs. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2008,70(2):439-444.

[13] Chen Huabing, Wan Jiangling*, Wang Yirui, Mou Dongsheng, Liu Hongbin,    Xu Huibi, Yang Xiangliang. A facile nanoaggregation strategy for oral delivery of hydrophobic drugs by utilizing acid-base neutralization reactions. NANOTECHNOLOGY, 2008,19(37):375104.

[14] Yi Tao, Wan Jiangling, Xu Huibi, Yang Xiangliang. Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2008,34(4-5):274-280.

发明专利

[1] 刘卫,万江陵,陈思渊,杨祥良. 辅酶Q10纳米脂质组合物及其制备方法和用途,CN201010557948.9(已授权).

[2] 万江陵,牟东升,周小顺,杨祥良,陈华兵,徐辉碧,刘卫. 一种伊曲康唑纳米结晶及其制备方法和应用,CN200910063819.1(已授权).

[3] 杨祥良,阮健,周小顺,万江陵,李进,贺容丽,王芳,朱吉胜,鲁珍娥,岳蓉,黄邦红. 一种中分子量羟乙基淀粉的合成方法,CN201110226792.0(已授权).

[4] 刘卫,万江陵,唐宇翔,周小顺,杨祥良. 一种提取浓缩S-腺苷蛋氨酸的方法,CN 201210065106.0(审查中).

[5] 刘卫,徐海波,陈云超,杨祥良,程欣,李欢,罗斌华,万江陵,周小顺. 体内相转变肿瘤靶向纳米泡及其制备方法和用途,CN 201210158275.9(审查中).

[6] 杨祥良,阮健,周小顺,万江陵,李进,贺容丽,王芳,朱吉胜,鲁珍娥,岳蓉,黄邦红. 一种中分子量羟乙基淀粉的洁净生产方法,CN201110226785.0(审查中).

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